Add the ground beef, and using a wooden spoon or spatula, break it apart into crumbles and brown it until it's cooked through. Pour off any excess fat then stir in the garlic powder, dried oregano, crushed red pepper flakes, tomato sauce, lasagna noodles, and a pinch of salt and pepper. Bring it to a boil then reduce the heat to medium-low, cover the pan securely and cook it until the noodles are soft, 18 to 20 minutes.